Selective reduction of organic compounds with indium hydride reagents
β Scribed by Masafumi Yamada; Koji Tanaka; Shuki Araki; Yasuo Butsugan
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 185 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Hydroxyketones and diketones have been reduced with lithium indium hydride to give meso-diols selectively, cΒ’-Hydroxyketones and 0c-diketones are reduced to meso-l,2-diols with high diastereoselectivities, whereas the selectivities of ~hydroxyketones and [~diketones are less satisfactory.
Dichloroindium hydride (Cl 2 InH), which was generated in situ by transmetallation between tributyltin hydride and indium trichloride, acted as a novel radical initiator for the reduction of organic halides with tributyltin hydride. The reaction was revealed to proceed through a radical process unde
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