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Selective deletion of p14(ARF) exon 1β of the INK4a locus in oral squamous cell carcinomas of Indians

✍ Scribed by M Viswanathan; N Tsuchida; G Shanmugam

Book ID
114393728
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
358 KB
Volume
37
Category
Article
ISSN
1368-8375

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Selective deletion of exon 1β of the p19
Selective deletion of exon 1β of the p19ARF gene in metastatic melanoma cell lines
✍ Rajiv Kumar; Ilari Sauroja; Kari Punnonen; Christer Jansen; Kari Hemminki 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 1 views

The INK4A locus on 9p21 is deleted or rearranged in a large number of human cancers. The locus encodes two unrelated and independently acting negative cell-cycle regulators, p16 and p19 ARF , arising in alternate reading frames from a partly shared sequence. We analyzed five human melanoma cell line