✦ LIBER ✦

Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib-resistant gastrointestinal stromal tumor

✍ Scribed by Toshirou Nishida; Tatsuo Kanda; Akiko Nishitani; Tsuyoshi Takahashi; Kiyokazu Nakajima; Takashi Ishikawa; Seiichi Hirota

Book ID: 108584126
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 790 KB
Volume: 99
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2008.00727.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular analysis of secondary kinase m

Molecular analysis of secondary kinase mutations in imatinib-resistant gastrointestinal stromal tumors

✍ Ken-Hong Lim; Ming-Jer Huang; Li-Tzong Chen; Tsang-En Wang; Chien-Liang Liu; Che 📂 Article 📅 2007 🏛 Springer US 🌐 English ⚖ 194 KB

Mutations of c-kit JM domain are found i

Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors

✍ Moskaluk, C A; Tian, Q; Marshall, C R; Rumpel, C A; Franquemont, D W; Jr, HF Fri 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 522 KB

Germline mutation in the juxtamembrane d

Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa

✍ Alessandro Beghini; MariaGrazia Tibiletti; Gaia Roversi; AnnaMaria Chiaravalli; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 491 KB 👁 2 views

Gain-of-function mutation at the extrace

Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours

✍ Seiichi Hirota; Toshirou Nishida; Koji Isozaki; Masahiko Taniguchi; Junichi Naka 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 2 views

Sunitinib-resistant gastrointestinal str

Sunitinib-resistant gastrointestinal stromal tumors harborcis-mutations in the activation loop of theKITgene

✍ Toshirou Nishida; Tsuyoshi Takahashi; Akiko Nishitani; Toshihiko Doi; Kuniaki Sh 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 451 KB

The analysis of status and clinical impl

The analysis of status and clinical implication of KIT and PDGFRA mutations in gastrointestinal stromal tumor (GIST)

✍ Chun-Yan Du; Ying-Qiang Shi; Ye Zhou; Hong Fu; Guangfa Zhao 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB 👁 1 views

## Abstract ## Background and objective to analyze the frequency and spectrum of KIT and platelet‐derived growth factor receptor‐alpha (PDGFRA) gene in a large series of study and to explore the clinical implication of mutations in the gastrointestinal stromal tumors (GISTs) in China. ## Method