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Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities

✍ Scribed by Secker-Walker, L M; Moorman, A V; Bain, B J; Mehta, A B


Book ID
110053845
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
47 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract We have identified a novel fusion partner of __MLL__, namely the mastermind like 2 (__MAML____2__ gene), in secondary acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with inv(11)(q21q23). RT‐PCR and sequencing revealed that exon 7 of __MLL__ was fused to exon 2 of __MAML

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