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Myelodysplastic syndromes associated with 11q23 abnormalities

โœ Scribed by Bain, B J; Moorman, A V; Johansson, B; Mehta, A B; Secker-Walker, L M

Book ID
110053844
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
159 KB
Volume
12
Category
Article
ISSN
0887-6924

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Rearrangements of the MLL gene at chromosome 11q23 are uncommon in de novo myelodysplastic syndrome (MDS). Here, we describe molecular findings in a patient with multilineage dysplasia and t(11;17)(q23;q25) who responded to decitabine therapy. Fluorescent in situ hybridization (FISH) demonstrated re