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High frequency of pro-B acute lymphoblastic leukemia in adults with secondary leukemia with 11q23 abnormalities

โœ Scribed by Ishizawa, S; Slovak, M L; Popplewell, L; Bedell, V; Wrede, J E; Carter, N H; Snyder, D S; Arber, D A


Book ID
110055463
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
107 KB
Volume
17
Category
Article
ISSN
0887-6924

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Ip;&-3qChromosome I I, band q23, is the frequent site of recurring cytogenetic rearrangements in human leukemia. We have cloned and sequenced the breakpoint junctions from a patient who had null-cell acute lymphoblastic leukemia (ALL) with a t( I 1;14)(q23;ql I). The chromosome 14 breakpoints occurr