Search for new moenomycin structure-activity relationships Synthesis of a trisaccharide precursor of a moenomycin analogue
✍ Scribed by Olaf Ritzeler; Lothar Hennig; Matthias Findeisen; Peter Welzel; Dietrich Müller
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 589 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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## Abstract A new approach for the synthesis of moenomycin trisaccharide analogues is reported in which three monosaccharide building blocks are used and allows the introduction of different substituents at the 6‐position of unit E (__Scheme 2__). Furthermore, a new procedure for the introduction a
## Abstract Routes allowing the synthesis of moenomycin analogues with one modified sugar component and with new lipid parts were developed (see **10c, 12c, 16b**, and **20b** in __Schemes 2__–__4__). It is anticipated that such analogues will be useful for studying the mode of action of the moenom