Studies on the Synthesis of Trisaccharide Analogues of the Antibiotic Moenomycin A
β Scribed by Guangbin Yang; Lothar Hennig; Matthias Findeisen; Ramona Oehme; Sabine Giesa; Peter Welzel
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- German
- Weight
- 292 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0018-019X
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β¦ Synopsis
Abstract
A new approach for the synthesis of moenomycin trisaccharide analogues is reported in which three monosaccharide building blocks are used and allows the introduction of different substituents at the 6βposition of unit E (Schemeβ 2). Furthermore, a new procedure for the introduction and manipulation of unit F is described (Schemeβ 3).
π SIMILAR VOLUMES
## Abstract Routes allowing the synthesis of moenomycin analogues with one modified sugar component and with new lipid parts were developed (see **10c, 12c, 16b**, and **20b** in __Schemesβ 2__β__4__). It is anticipated that such analogues will be useful for studying the mode of action of the moenom