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Search for human herpesvirus 6 DNA in cerebrospinal fluid from AIDS patients with progressive multifocal leukoencephalopathy

✍ Scribed by Iñigo Corral; Carmen Quereda; María Jesús Pérez-Elías; Santiago Moreno


Book ID
111739173
Publisher
Springer US
Year
2003
Tongue
English
Weight
83 KB
Volume
9
Category
Article
ISSN
1355-0284

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Progressive multifocal leukoencephalopathy (PML) is a lytic infection of oligodendrocytes by the human papovavirus JC. Patients with defects in cell-mediated immunity are at risk for active disease: a usually lethal demyelination of the brain. PML develops in at least 4% of patients with the acquire