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Scavenging capacities of some thiazolyl thiazolidine-2,4-dione compounds on superoxide radical, hydroxyl radical, and DPPH radical

✍ Scribed by Irena Kruk; Oya Bozdağ-Dündar; Meltem Ceylan-Ünlüsoy; Rahmiye Ertan; Hassan Y. Aboul-Enein; Teresa Michalska

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
288 KB
Volume
24
Category
Article
ISSN
1522-7235

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✦ Synopsis

Abstract

The scavenging effects of eighteen thiazolyl thiazolidine‐2,4‐dione compounds (TTCs) on superoxide radical
, hydroxyl radical HO^•^, and 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH^•^) radical were evaluated by the chemiluminescence technique, electron spin resonance spectrometry (ESR) and visible spectrophotometry, respectively. The examined compounds were shown to have 27–59%
scavenging ability, 19–69% HO^•^ scavenging activity and 2–32% DPPH^•^ scavenging ability. This property of the tested compound seems to be important in the prevention of various diseases of free radicals etiology. Copyright © 2009 John Wiley & Sons, Ltd.

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