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Free radical scavenging abilities of flavonyl-thiazolidine-2,4-dione compounds

✍ Scribed by Oya Bozdağ-Dündar; Rahmiye Ertan; Hassan Y. Aboul-Enein; Aleksandra Kładna; Irena Kruk

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
414 KB
Volume
26
Category
Article
ISSN
1522-7235

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✦ Synopsis

Abstract

Free radical scavenging activity of flavonyl‐thiazolidine‐2,4‐dione compounds has been evaluated using chemiluminescence, electron spin resonance spectroscopy with 5,5‐dimethyl‐1‐pyrroline‐1‐oxide as spin trap and DPPH (2,2′‐diphenyl‐1‐picrylhydrazyl) method. The examined compounds exhibited 28–50% scavenging superoxide anion radical (${\rm{O}}_2^{\bar\bullet}$), 16.7–76.7% hydroxyl radical (HO^•^) and 9–40% DPPH radical. Compounds containing carbonyl group in their structure can be considered as antioxidants with high relevance and great biological importance. Copyright © 2009 John Wiley & Sons, Ltd.

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