𝔖 Bobbio Scriptorium
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S.16.03 Alpha-synuclein and Lewy body diseases


Book ID
118591638
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
237 KB
Volume
15
Category
Article
ISSN
0924-977X

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Alpha-synuclein dysfunction in Lewy body
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alpha-Synuclein belongs to a small group of natively unfolded proteins that can transiently bind to lipid membranes and acquire a partial alpha-helical conformation. Its relevance to Parkinson's disease (PD) is based on mutations found in familial cases of the disease and its presence in filaments o