(S)-Benzyl 2-[N-(5-chloropyridin-2-yl)carbamoyl]pyrrolidine-1-carboxylate
✍ Scribed by He, Long
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 394 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
In the title compound, C~18~H~18~ClN~3~O~3~, the pyrrolidine ring adopts an envelope conformation. The dihedral angle between the phenyl ring and the pyridine ring is 28.30 (7)°. The crystal packing is stabilized by N—H...O and C—H...O hydrogen bonding.
📜 SIMILAR VOLUMES
The molecules of the title compound, C 19 H 21 N 3 O 3 , are linked by a hydrogen bond between the amide NH group and the ester substituent in the 1-position of the pyrrolidine ring. This gives rise to a helical chain that propagates along the a axis of the orthorhombic cell by a 2 1 screw translati
In the title compound, C 19 H 21 N 3 O 3 , the pyrrolidine ring possesses an envelope conformation. The crystal packing is stabilized by N-HÁ Á ÁO and C-HÁ Á ÁO hydrogen bonds.
In the title compound, C 11 H 20 N 2 O 3 , the pyrrolidine ring adopts an envelope conformation, where the acetoxy and carbamoyl groups are equatorial. Each molecule interacts, through strong N-HÁ Á ÁO hydrogen bonds, with two adjacent molecules.
In the title compound, C 13 H 14 N 2 O 3 SÁH 2 O, the benzoyl group lies out of the plane of the N 2 CS thiourea unit, having a C carbonyl -N-C-S torsion angle of 119.4 (4) . The crystal structure is stabilized by N-HÁ Á ÁO, O-HÁ Á ÁO, C-HÁ Á ÁO and C-HÁ Á ÁS intermolecular hydrogen bonds, forming a
The title compound, C~17~H~18~N~2~O~7~, is a synthetic racemic analogue of lactivicin, a natural product antibiotic that targets penicillin-binding proteins. There are two almost identical molecules in the asymmetric unit.