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4-Nitro­benzyl 5-oxo-2-(2-oxopiperidin-1-yl)tetra­hydro­furan-2-carboxyl­ate

✍ Scribed by Shanley, Samantha J. ;Schofield, Christopher J. ;Coles, Simon J. ;Watkin, David J. ;Fischer, Delphine S.

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
522 KB
Volume
63
Category
Article
ISSN
1600-5368

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound, C~17~H~18~N~2~O~7~, is a synthetic racemic analogue of lactivicin, a natural product antibiotic that targets penicillin-binding proteins. There are two almost identical molecules in the asymmetric unit.

📜 SIMILAR VOLUMES

Methyl 1,6-dimethyl-4-(3-nitro­phen­yl)-
Methyl 1,6-dimethyl-4-(3-nitro­phen­yl)-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
✍ Li, Jian-Jun ;Jiang, Lai ;Wu, Xue-Ping ;Su, Wei-Ke 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 325 KB

Single-crystal X-ray study T = 298 K Mean (C-C) = 0.005 A R factor = 0.087 wR factor = 0.168 Data-to-parameter ratio = 12.5 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

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()-2-Oxo-4-(2-oxo-2-phenyl­ethyl)-5-phenyl­tetra­hydro­furan-3-carboxyl­ic acid
✍ Greatrex, Ben W. ;Kimber, Marc C. ;Taylor, Dennis K. ;Fallon, Gary D. 📂 Article 📅 2002 🏛 International Union of Crystallography 🌐 English ⚖ 153 KB

The stereochemistry about the lactone ring system of the title compound, C 19 H 16 O 5 , has been established. Intermolecular hydrogen bonds are observed between carboxylic acid groups.

Ethyl 4-(4-hydroxy­phenyl)-6-methyl-2-ox
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✍ Li, Ming ;Guo, Wei-Si ;Wen, Li-Rong ;Qi, Wen-Ying 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 150 KB

Single-crystal X-ray study T = 293 K Mean (C±C) = 0.003 A Ê Disorder in main residue R factor = 0.043 wR factor = 0.134 Data-to-parameter ratio = 12.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.