()-2-Oxo-4-(2-oxo-2-phenylethyl)-5-phenyltetrahydrofuran-3-carboxylic acid
✍ Scribed by Greatrex, Ben W. ;Kimber, Marc C. ;Taylor, Dennis K. ;Fallon, Gary D.
- Publisher
- International Union of Crystallography
- Year
- 2002
- Tongue
- English
- Weight
- 153 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The stereochemistry about the lactone ring system of the title compound, C 19 H 16 O 5 , has been established. Intermolecular hydrogen bonds are observed between carboxylic acid groups.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 293 K Mean (C±C) = 0.003 A Ê Disorder in main residue R factor = 0.043 wR factor = 0.134 Data-to-parameter ratio = 12.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
In the title compound, C 18 H 21 NO 4 , the molecules form dimers by means of a pair of NÐHÁ Á ÁO hydrogen bonds. The 2(1H)pyridone ring displays a screw±boat conformation.
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.005 A Ê R factor = 0.045 wR factor = 0.140 Data-to-parameter ratio = 13.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The title compound, C~17~H~18~N~2~O~7~, is a synthetic racemic analogue of lactivicin, a natural product antibiotic that targets penicillin-binding proteins. There are two almost identical molecules in the asymmetric unit.