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Role of polyamines in isoproterenol-induced cardiac hypertrophy: Effects of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase

✍ Scribed by Jorge V Bartolome; Patricia A Trepanier; Elise A Chait; Theodore A Slotkin


Book ID
118915457
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
412 KB
Volume
14
Category
Article
ISSN
0022-2828

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D,L-α-DIFLUOROMETHYLORNITHINE, AN IRREVE
✍ Shailesh Kumar Choudhary; Dipali Sharma; Aparna Dixit 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 171 KB

In the present study, the effect of D,L-alpha-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), on Friend's murine erythroleukemia (MEL) cell differentiation is investigated. DFMO was able to induce differentiation of MEL cells in culture as determined by ha