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Subcellular distribution of ornithine decarboxylase in rat liver and accessibility of the enzyme to α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase

✍ Scribed by Jacques Bartholeyns


Book ID
118942313
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
410 KB
Volume
32
Category
Article
ISSN
0024-3205

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D,L-α-DIFLUOROMETHYLORNITHINE, AN IRREVE
✍ Shailesh Kumar Choudhary; Dipali Sharma; Aparna Dixit 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 171 KB

In the present study, the effect of D,L-alpha-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), on Friend's murine erythroleukemia (MEL) cell differentiation is investigated. DFMO was able to induce differentiation of MEL cells in culture as determined by ha