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Role of Phase I enzymes in benzo(a)pyrene (BP)-DNA adduct formation in normal human mammary epithelial cells (NHMECS)

✍ Scribed by R. Divi; T. Einem; M. Shockley; M. Verma; M. Poirier


Book ID
116923185
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
71 KB
Volume
196
Category
Article
ISSN
0378-4274

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## Abstract We hypothesized that chlorophyllin (CHLN) would reduce benzo[__a__]pyrene‐DNA (BP‐DNA) adduct levels. Using normal human mammary epithelial cells (NHMECs) exposed to 4 ΞΌM BP for 24 hr in the presence or absence of 5 ΞΌM CHLN, we measured BP‐DNA adducts by chemiluminescence immunoassay (C