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Role of Genetics in Tests of Genotype, Status, and Disease Progression in Early-Onset Alzheimer’s Disease

✍ Scribed by P.H. St George-Hyslop

Book ID
117414302
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
90 KB
Volume
19
Category
Article
ISSN
0197-4580

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✍ Ephrat Levy-Lahad; Amnon Lahad; Ellen M. Wijsman; Thomas D. Bird; Dr Gerard D. S 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB 👁 2 views

## Abstract The effect of the apolipoprotein E (APOE) ϵ4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage