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Role of endothelin-1 in hypertension

✍ Scribed by Marc Iglarz; Ernesto L. Schiffrin


Book ID
107541159
Publisher
Springer
Year
2003
Tongue
English
Weight
339 KB
Volume
5
Category
Article
ISSN
1522-6417

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Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular diseases. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the av