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Plasma endothelin-1 levels in patients with biliary atresia: possible role in development of portal hypertension

โœ Scribed by V. Chongsrisawat; P. Chatchatee; R. Samransamruajkit; P. Vanapongtipagorn; P. Chottivittayatarakorn; Y. Poovorawan

Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
208 KB
Volume
19
Category
Article
ISSN
0179-0358

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We studied the acute effects of ketanserin, a serotonin Sz antagonist, on systemic and splanchnic hemodynamics in 11 patients with cirrhosis. Mean arterial pressure decreased moderately but significantly after ketanserin. This effect was maximal at 6 min and correlated to the severity of cirrhosis.