✦ LIBER ✦

Role of endothelin-1 in diabetes mellitus

✍ Scribed by Sármán, Beatrix ;Tóth, Miklós ;Somogyi, Anikó

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 42 KB
Volume: 14
Category: Article
ISSN: 0742-4221
DOI: 10.1002/(sici)1099-0895(199806)14:2<171::aid-dmr207>3.0.co;2-g

No coin nor oath required. For personal study only.

✦ Synopsis

Endothelin-1 is mainly synthesized by the vascular endothelial cells and acts on the vascular smooth muscle. Because of its vasoconstrictor and mitogenic effects it plays a role in the development of vascular diseases. In diabetes mellitus atherosclerosis is accelerated. The authors summarize the available data of the role of endothelin-1 in Type 1 and Type 2 diabetes mellitus and the development of diabetic complication.

📜 SIMILAR VOLUMES

Needle Phobia in Type 1 Diabetes Mellitu

Needle Phobia in Type 1 Diabetes Mellitus

✍ Zambanini, A.; Feher, M.D. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB 👁 1 views

Needle phobia in patients with Type 1 (insulin-dependent) diabetes mellitus is difficult to manage. We report a case of long-standing needle phobia in a patient with 33 years of Type 1 diabetes mellitus who has developed very few vascular complications. Further studies are required to identify the p

Role of protein kinases in mediating dia

Role of protein kinases in mediating diabetes-induced augmented vasoconstriction to endothelin-1 in the renal arteries of STZ-diabetic rats

✍ Mariam H. M. Yousif 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

Autonomic function in children with Type

Autonomic function in children with Type 1 diabetes mellitus

✍ Tanaka, H.; Hyllienmark, L.; Thulesius, O.; Brismar, T.; Ludvigsson, J.; O.Erics 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 149 KB 👁 1 views

We investigated autonomic function in 58 children and young adults with Type 1 diabetes mellitus (aged 7-22 years, duration from 3 to 18, 8.6 ± 3.4 years) and in 74 healthy controls (6-21 years) using power spectral analysis of blood pressure and heart rate in addition to conventional standard auton

Role of non-esterified fatty acids in th

Role of non-esterified fatty acids in the pathogenesis of Type 2 diabetes mellitus

✍ Paolisso, G.; Howard, B.V. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 2 views

Over 30 years after the original description of Randle's cycle, the mechanisms by which elevated circulating non-esterified fatty acids might be causally related to glucose intolerance in Type 2 diabetes mellitus remain uncertain. This review examines the evidence that elevated plasma NEFA can inhib

Role of endothelin in disseminated intra

Role of endothelin in disseminated intravascular coagulation

✍ H. Asakura; H. Jokaji; M. Saito C. Uotani; I. Kumabashiri; E. Morishita; M. Yama 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB 👁 2 views

Onset of Type 1 diabetes mellitus in inf

Onset of Type 1 diabetes mellitus in infancy after enterovirus infections

✍ Lönnrot, M.; Knip, M.; Roivainen, M.; Koskela, P.; Åkerblom, H.K.; Hyöty, H. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 48 KB 👁 1 views

Enterovirus infections may initiate and accelerate the beta-cell damaging process leading to Type 1 (insulin-dependent) diabetes mellitus (Type 1 DM). Recent prospective studies have suggested that this can happen long before overt disease and even in utero. We describe an infant, followed regularly