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Risk variants inBMP4promoters for nonsyndromic cleft lip/palate in a Chilean population

✍ Scribed by José Suazo; Julio C Tapia; José Luis Santos; Víctor G Castro; Alicia Colombo; Rafael Blanco

Book ID
115009220
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
501 KB
Volume
12
Category
Article
ISSN
1471-2350

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Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population: Evidence for IRF6 and variants at 8q24 and 10q25
✍ Augusto Rojas-Martinez; Heiko Reutter; Oscar Chacon-Camacho; Rafael B. R. Leon-C 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 2 views

## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2