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Ring-Closing Metathesis of Chiral Allylamines. Enantioselective Synthesis of (2 S ,3 R ,4 S )-3,4-Dihydroxyproline

✍ Scribed by Martín, Rubén; Alcón, Montserrat; Pericàs, Miquel A.; Riera, Antoni


Book ID
126254935
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
112 KB
Volume
67
Category
Article
ISSN
0022-3263

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Stereoselective synthesis of 1,4-dideoxy
✍ A Madhan; B Venkateswara Rao 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 123 KB

A stereoselective synthesis of 1,4-dideoxy-1,4-imino-D-allitol 1 and formal synthesis of (2S,3R,4S)-3,4-dihydroxyproline was achieved via the addition of vinylmagnesium bromide to the benzylimine derived from (R)-2,3-O-isopropylidene glyceraldehyde followed by N-allylation, ring-closing metathesis (