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Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2

✍ Scribed by Courtney Netherland; Douglas P. Thewke


Book ID
116300545
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
516 KB
Volume
398
Category
Article
ISSN
0006-291X

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The pharmacokinetics of 3-(decyldimethylsilyI)-N-[2-(4-methylphenyl)-lphenylethyllpropanamide (DMPP), an inhibitor of acyl-CoA:cholesterol acyltransferase, have been studied in the dog and the rat using "C and 'H dual-labelled drug. In both species, gastrointestinal absorption of DMPP was slow and