Rhenium-Catalyzed 1,3-Isomerization of Allylic Alcohols: Scope and Chirality Transfer.
✍ Scribed by Christie Morrill; Gregory L. Beutner; Robert H. Grubbs
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 55 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract **Nothing to sm(Ir)k at**: Under appropriate reaction conditions, iridium hydride catalysts promote the isomerization of primary allylic alcohols. The best catalysts, like (__R__)‐**1** (P green, O red, N blue, Ir yellow), deliver the desired chiral aldehydes with excellent enantioselec
## Abstract Treatment of allylic alcohols containing a 1,1‐disubstituted alkene with a palladium catalyst and hydrogen gas (1 bar) results in facile isomerization to their corresponding trisubstituted (__E__)‐allylic alcohols, along with small amounts of the corresponding hydrogenated products.
## Abstract **Unter sehr milden Reaktionsbedingungen** vermitteln Iridiumhydridkatalysatoren die Isomerisierung primärer Allylalkohole. Die besten Katalysatoren, darunter (__R__)‐**1**, liefern die gewünschten chiralen Aldehyde mit ausgezeichneten Enantioselektivitäten und in guten Ausbeuten. Auf d