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Retinoic Acid Induces the Degradation of the Leukemogenic Protein Encoded by the Promyelocytic Leukemia Gene Fused to the Retinoic Acid Receptor α Gene

✍ Scribed by George Wolf; Cynthia M. Smas


Book ID
111435375
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
356 KB
Volume
58
Category
Article
ISSN
0029-6643

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A human genomic fragment comprising the cellular retinoic acid binding protein (CRABP) gene was isolated. By using a panel of somatic cell hybrids, this gene could be assigned to human chromosome 15. Subsequently, a possible involvement of the CRABP gene in translocation (15;17) (q22;q11) positive a