𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Resolution of terfenadine enantiomers by reversed phase-high performance liquid chromatography using β-cyclodextrin as mobile phase additive

✍ Scribed by Sekhar Surapaneni; Shoukry K.W. Khalil


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
252 KB
Volume
14
Category
Article
ISSN
0731-7085

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Resolution of terfenadine enantiomers by
✍ Henri Weems; Kaveh Zamani 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB 👁 1 views

Enantiomers of terfenadine were resolved by high-performance liquid chromatography (HF'LC) using a chiral stationary phase (CSP) column packed with p-cyclodextrin (p-CD) covalently bound to silica. Separation was achieved in both the reverse phase and normal phase modes. Resolution of enantiomers wa

Separation of enantiomers by microcolumn
✍ Rongzong Hu; Toyohide Takeuchi; Ji-Ye Jin; Tomoo Miwa 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 606 KB

Enantiomers can be separated by microcolumn liquid chromatography with methylated &cyclodextrin @-CD) as a mobile phase additive. Effects of the mobile phase composition on the retention behaviour of the analytes were examined. The separation factor achieved with heptakis(2,3,6-tri-0-methyl)+-CD as

On-line recovery of trimeprazine enantio
✍ A.D. Cooper; T.M. Jefferies 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 282 KB

A procedure is described which allows the on-line recovery of enantiomers following semi-preparative chiral separation by RP-HPLC using beta-cyclodextrin in the mobile phase. By this method, the phenothiazine antihistamine trimeprazine (I) was resolved into its antipodes at greater than 95% optical