𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Resolution of terfenadine enantiomers by β-cyclodextrin chiral stationary phase high-performance liquid chromatography

✍ Scribed by Henri Weems; Kaveh Zamani

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
473 KB
Volume
4
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.

✦ Synopsis

Enantiomers of terfenadine were resolved by high-performance liquid chromatography (HF'LC) using a chiral stationary phase (CSP) column packed with p-cyclodextrin (p-CD) covalently bound to silica. Separation was achieved in both the reverse phase and normal phase modes. Resolution of enantiomers was confirmed by ultraviolet-visible absorption, circular dichroism, and mass spectral analysis.

📜 SIMILAR VOLUMES

Enantiomeric separation of d-/l-norepine
Enantiomeric separation of d-/l-norepinephrine and -epinephrine by high-performance liquid chromatography with a β-cyclodextrin type chiral stationary phase
✍ Takeshi Fukushima; Katsuhisa Murayama; Tomofumi Santa; Hiroshi Homma; Kazuhiro I 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 61 KB 👁 2 views

Enantiomeric separation of d-/l-norepinephrine (NE) and d-/l-epinephrine (E) was investigated with various mobile phases by high-performance liquid chromatography using a ␤-cyclodextrin type chiral stationary phase as a chiral column. The mobile phase of 2.5 M phosphate buffer (pH 3.0) gave separati

High-performance liquid chromatography s
High-performance liquid chromatography separation of enantiomers of mandelic acid and its analogs on a chiral stationary phase
✍ Ritu Aneja; Pratibha Mehta Luthra; Satinder Ahuja 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 1 views

## Abstract The enantiomers of mandelic acid and its analogs have been chromatographically separated on a chiral stationary phase (CSP) derived from 4‐(3,5‐dinitrobenzamido) tetrahydrophenanthrene. The rationale of separations of these compounds is discussed with respect to the method development f