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Resolution of racemic ketoprofen in organic solvents by lipase fromBurkholderia cepaciaG63

โœ Scribed by Xiang Li, Tao Liu, Li Xu, Xiaohua Gui, Feng Su, Yunjun Yan


Book ID
118824793
Publisher
The Korean Society for Biotechnology and Bioengineering
Year
2012
Tongue
English
Weight
403 KB
Volume
17
Category
Article
ISSN
1226-8372

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Resolution of racemic flurbiprofen by li
โœ Raffaele Morrone; Giovanni Nicolosi; Angela Patti; Mario Piattelli ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 357 KB

Resolution of rac-flurbiprofen, 2-fluoro-0t-methyi-[1,1'-biphenyl]-4-scetic acid (1), by biocatalytic methodologies has been studied. Enzymatic hydrolysis of rac-flurbiprofen methyl ester (2) in aqueous-organic medium gave poor results. Transesterification of the same ester mediated by immobilized l