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Resolution of Racemic Acids by Irreversible Lipase-Catalyzed Esterification in Organic Solvents

โœ Scribed by Raffaele Morrone; Mario Piattelli; Giovanni Nicolosi


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
213 KB
Volume
2001
Category
Article
ISSN
1434-193X

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The lipase-catalyzed irreversible transesterification procedure using vinyl esters was applied to the resolution of racemic 2-phenoxypropanoic acids. Aspergillus niger lipase showed high enantioselectivities and reasonable reaction rates. The enantioselectivity was found to be affected profoundly by