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Resolution of a protein sequence ambiguity by X-ray crystallographic and mass spectrometric methods

✍ Scribed by Keefe, L. J. ;Lattman, E. E. ;Wolkow, C. ;Woods, A. ;Chevrier, M. ;Cotter, R. J.


Book ID
114500569
Publisher
International Union of Crystallography
Year
1992
Tongue
English
Weight
501 KB
Volume
25
Category
Article
ISSN
0021-8898

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Total synthesis by modern chemical ligat
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## Abstract The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic prod