Residual Antigen Presentation after Influenza Virus Infection Affects CD8 T Cell Activation and Migration
✍ Scribed by David J. Zammit; Damian L. Turner; Kimberly D. Klonowski; Leo Lefrançois; Linda S. Cauley
- Book ID
- 116570554
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 823 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1074-7613
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The antigen recognized by the DX5 antibody (DX5 antigen) is expressed on all murine NK cells. In the present study we found that a proportion of CD8 + T cells ( ˚5%) also express the DX5 antigen in uninfected mice, and that numbers of CD8 + T cells expressing DX5 are significantly higher in the lung
## Abstract CD8+T lymphocytes activated in peripheral lymphoid organs are believed to preferentially localize to the hepatic sinusoids, but the role of antigen in the process has been difficult to define. To create experimental mice in which the liver was unique in lacking the ability to present an