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IFN-γ production downstream of NKT cell activation in mice infected with influenza virus enhances the cytolytic activities of both NK cells and viral antigen-specific CD8+ T cells

✍ Scribed by Hiroki Ishikawa; Kazuo Tanaka; Etsuko Kutsukake; Toshie Fukui; Hiraku Sasaki; Akihiro Hata; Satoshi Noda; Tetsuya Matsumoto

Book ID
113948173
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
862 KB
Volume
407
Category
Article
ISSN
0042-6822

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✍ Nuria Tormo; Carlos Solano; Isabel Benet; José Nieto; Rafael de la Cámara; Ana G 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB

## Abstract The dynamics of CMV pp65 and IE‐1‐specific IFNγ‐producing CD8^+^ (IFNγ CD8^+^) and CD4^+^ (IFNγ CD4^+^) T cells and CMV DNAemia were assessed in 19 pre‐emptively treated episodes of active CMV infection. Peripheral counts of IFNγ CD8^+^ and IFNγ CD4^+^ T cells inversely correlated with