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Replication-Independent Repair of DNA Interstrand Crosslinks

✍ Scribed by Hannah L. Williams; Max E. Gottesman; Jean Gautier

Book ID: 111906113
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 173 KB
Volume: 47
Category: Article
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2012.05.001

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## Abstract DNA damage by agents crosslinking the strands presents a formidable challenge to the cell to repair for survival and to repair accurately for maintenance of genetic information. It appears that repair of DNA crosslinks occurs in a path involving double strand breaks (DSBs) in the DNA. M