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Relationship between anti–double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus

✍ Scribed by Matthew D. Linnik; Jay Z. Hu; Kenneth R. Heilbrunn; Vibeke Strand; Frank L. Hurley; Tenshang Joh; LJP 394 Investigator Consortium


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
238 KB
Volume
52
Category
Article
ISSN
0004-3591

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We describe a patient with systemic lupus erythematosus who, after a disease flare, sequentially produced antibodies to specific Sm polypeptides (demonstrated by counterimmunoelectrophoresis, immunoblotting, and RNA immunoprecipitation) concomitantly with the disappearance of anti-double-stranded DN