Decreases in anti–double-stranded DNA levels are associated with concurrent flares in patients with systemic lupus erythematosus
✍ Scribed by Audrey Ho; Laurence S. Magder; Susan G. Barr; Michelle Petri
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 100 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To identify the prevalence of serologically active clinically quiescent (SACQ) patients in a cohort of 290 patients with systemic lupus erythematosus (SLE). We investigated if the presence of anti–double‐stranded DNA (anti‐dsDNA) or antinucleosome (anti‐NCS) antibodies dur
Objective. To determine the degree to which changes in C3 and C4 precede or coincide with changes in systemic lupus erythematosus (SLE) activity, as measured by 5 global activity indices, the physician's global assessment (PGA), modified SLE Disease Activity Index (M-SLEDAI), modified Lupus Activity
We describe a patient with systemic lupus erythematosus who, after a disease flare, sequentially produced antibodies to specific Sm polypeptides (demonstrated by counterimmunoelectrophoresis, immunoblotting, and RNA immunoprecipitation) concomitantly with the disappearance of anti-double-stranded DN