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Estrogen enhancement of anti–double-stranded DNA antibody and immunoglobulin G production in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

✍ Scribed by Naoko Kanda; Tetsuya Tsuchida; Kunihiko Tamaki


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
196 KB
Volume
42
Category
Article
ISSN
0004-3591

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We describe a patient with systemic lupus erythematosus who, after a disease flare, sequentially produced antibodies to specific Sm polypeptides (demonstrated by counterimmunoelectrophoresis, immunoblotting, and RNA immunoprecipitation) concomitantly with the disappearance of anti-double-stranded DN