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Regulation of sterol biosynthesis in yeast: Induction of 3-hydroxy-3-methylglutaryl-CoA reductase by glucose

✍ Scribed by J. Berndt; M. Boll; M. Löwel; R. Gaumert

Book ID: 118853679
Publisher: Elsevier Science
Year: 1973
Tongue: English
Weight: 306 KB
Volume: 51
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(73)90003-x

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## Abstract Elevated 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase expression supports synthesis of prenyl pyrophosphate intermediates required for tumor growth. In this study, the copy number of HMG‐CoA reductase mRNA was determined in solid tumor and leukemic cell lines using competit