Desensitization of the nicotinic acetylc
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Eldefrawi, Mohyee E. ;Schweizer, Gordon ;Bakry, Nabil M. ;Valdes, James J.
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Article
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1988
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John Wiley and Sons
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English
β 615 KB
The interaction of diisopropylfluorophosphate (DFP) with the nicotinic acetylcholine (ACh) receptor of Torpedo electric organ was studied, using [3H]-phencyclidine ([3H]-PCP) as a reporter probe. Phencyclidine binds with different kinetics to resting, activated, and desensitized receptor conformatio