Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels
โ Scribed by Sergio Elenes; Anthony Auerbach
- Book ID
- 110111699
- Publisher
- Cambridge University Press
- Year
- 2002
- Tongue
- English
- Weight
- 591 KB
- Volume
- 541
- Category
- Article
- ISSN
- 0022-3751
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The interaction of diisopropylfluorophosphate (DFP) with the nicotinic acetylcholine (ACh) receptor of Torpedo electric organ was studied, using [3H]-phencyclidine ([3H]-PCP) as a reporter probe. Phencyclidine binds with different kinetics to resting, activated, and desensitized receptor conformatio
MK-801 is a potent inhibitor of the NMDA subtype of glutamate receptors. Single-channel and macroscopic currents indicate that MK-801 also inhibits nicotinic acetylcholine receptors (nAChRs). MK-801 does not significantly increase desensitization of the nAChRs or compete for the ACh binding site. Al
The rate of desensitization of nicotinic acetylcholine (ACh) receptor (nAChR), an important characteristic of nAChR function, was studied in myotubes of the mouse C2C12 cell line at different times after fusion, by measuring the decay of ACh-evoked currents (IAch) under various patch-clamp configura