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Regulation of IGF-1 receptors on rabbit articular chondrocytes by inflammatory mediators

✍ Scribed by S. Blount; A. Crawford

Book ID
105427788
Publisher
SP Birkhäuser Verlag Basel
Year
1994
Tongue
English
Weight
198 KB
Volume
41
Category
Article
ISSN
1420-908X

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## Abstract Endothelin (ET) receptors on chondrocytes were demonstrated using cultured rabbit costal chondrocytes. After crosslinking the receptors on the cells with ^125^ I‐ET‐1, two major bands of 43 kDa and 46 kDa were separated by SDS‐PAGE. Scatchard analysis demonstrated two classes of ET rece