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Regulation of DNA-dependent protein kinase activity in leukemic cells

โœ Scribed by Muller, Catherine; Salles, Bernard

Book ID
110060982
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
375 KB
Volume
15
Category
Article
ISSN
0950-9232

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We report a linkage between cell aggressiveness, protein kinase C (PKC) activity, tyrosine kinase (PTK) activity and serum requirement. We used 2 leukemic cell lines induced by Moloney murine leukemia virus (MLV). One line was highly aggressive (8s-24-I) and required low serum concentrations (3%) fo