Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells
β Scribed by Olsen, B B; Issinger, O-G; Guerra, B
- Book ID
- 109972507
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 913 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0950-9232
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## Abstract DNAβdependent protein kinase (DNAβPK), a nuclear serine/threonine kinase, is responsible for the DNA doubleβstrand break repair. Cells lacking or with dysfunctional DNAβPK are often associated with misβrepair, chromosome aberrations, and complex exchanges, all of which are known to cont
## Abstract Protein kinase CK2 is a ubiquitous protein serine/threonine kinase that is involved in cell growth and proliferation as well as suppression of apoptosis. Several studies have suggested that the kinase plays a role in cell cycle progression; however, changes in enzyme activity during pha