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Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by parathyroid hormone and cAMP-agonists

✍ Scribed by J.P.T.M. van Leeuwen; J.C. Birkenhäger; T. Vink-van Wijngaarden; G.J.C.M. van den Bemd; H.A.P. Pols

Book ID
115765509
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
835 KB
Volume
185
Category
Article
ISSN
0006-291X

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu