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Evidence for coordinated regulation of osteoblast function by 1,25-dihydroxyvitamin D3 and parathyroid hormone

✍ Scribed by Johannes P.T.M. van Leeuwen; Jan C. Birkenhager; Gertjan C.M. van den Bemd; Huibert A.P. Pols


Book ID
116106425
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
1005 KB
Volume
1312
Category
Article
ISSN
0167-4889

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu