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Regioselectivity in the alkylation of metalated α.β-unsaturated aldimines

✍ Scribed by Kunihiko Takabe; Hidenori Fujiwara; Takao Katagiri; Juntaro Tanaka

Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
102 KB
Volume
16
Category
Article
ISSN
0040-4039

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✦ Synopsis

The reactions of a-lithiated saturated aldimines with various electrophiles have been widely utilized to synthesize a variety of organic compounds. l-4) To our knowledge, the alkylation of the metalated a,b-unsaturated aldimines has not been reported. In this communication we wish to report on the regioselectivity in the alkylation and trimethylsilylation of the lithiated a,!3unsaturated aldimines and on the application to the synthesis of terpenoids.

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