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Alkylation of α,β-unsaturated amides via metalated and dimetalated intermediates

✍ Scribed by J.A. Oakleaf; M.T. Thomas; A. Wu; V. Snieckus


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
239 KB
Volume
19
Category
Article
ISSN
0040-4039

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✍ Kunihiko Takabe; Hidenori Fujiwara; Takao Katagiri; Juntaro Tanaka 📂 Article 📅 1975 🏛 Elsevier Science 🌐 French ⚖ 102 KB

The reactions of a-lithiated saturated aldimines with various electrophiles have been widely utilized to synthesize a variety of organic compounds. l-4) To our knowledge, the alkylation of the metalated a,b-unsaturated aldimines has not been reported. In this communication we wish to report on the r