𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reduced Ischemic Brain Injury in Interleukin-1?? Converting Enzyme-Deficient Mice

✍ Scribed by Schielke, Gerald P.; Yang, Guo-Yuan; Shivers, Brenda D.; Betz, A. Lorris

Book ID
110078865
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
391 KB
Volume
18
Category
Article
ISSN
0271-678X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Characterization of mice deficient in in
Characterization of mice deficient in interleukin-1Ξ² converting enzyme
✍ Ping Li; Hamish Allen; Subhashis Banerjee; Tara Seshadri πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 1 views

Interleukin-1b converting enzyme (ICE) processes the inactive proIL-1b to the proinflammatory mature IL-1b. ICE belongs to a family of cysteine proteases that have been implicated in apoptosis. To address the biological functions of ICE, we generated ICE-deficient mice through gene targeting technol

Reduced brain injury in CD18-deficient m
Reduced brain injury in CD18-deficient mice after experimental intracerebral hemorrhage
✍ Elena Titova; Robert P. Ostrowski; Christopher G. Kevil; Wenni Tong; Hugo Rojas; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 320 KB

## Abstract Many studies have indicated leukocytes are a major contributor to brain injuries caused by intracerebral hemorrhage (ICH). Leukocyte‐expressed CD18 is important for neutrophil–endothelial interactions in the vasculature, and CD18 deficiency protects against ischemia‐reperfusion injury.

Strongly compromised inflammatory respon
Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice
✍ Milena Penkowa; Torben Moos; Javier Carrasco; Hanne Hadberg; Amalia Molinero; Ho πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 710 KB

Injury to the central nervous system (CNS) elicits an inflammatory response involving activation of microglia, brain macrophages, and astrocytes, processes likely mediated by the release of proinflammatory cytokines. In order to determine the role of interleukin-6 (IL-6) during the inflammatory resp