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Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2

✍ Scribed by Bonventre, Joseph V.; Huang, Zhihong; Taheri, M. Reza; O'Leary, Eileen; Li, En; Moskowitz, Michael A.; Sapirstein, Adam


Book ID
109793589
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
296 KB
Volume
390
Category
Article
ISSN
0028-0836

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Reduced brain injury in CD18-deficient m
✍ Elena Titova; Robert P. Ostrowski; Christopher G. Kevil; Wenni Tong; Hugo Rojas; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 320 KB

## Abstract Many studies have indicated leukocytes are a major contributor to brain injuries caused by intracerebral hemorrhage (ICH). Leukocyte‐expressed CD18 is important for neutrophil–endothelial interactions in the vasculature, and CD18 deficiency protects against ischemia‐reperfusion injury.